The Neurologic Wellness Podcast
Episode 114: Understanding Therapeutic Plasma Exchange
– with Dr. Peter Miller
In this episode, we interview Dr. Peter Miller of VIP TPE in Boca Raton, Florida, to explore the science and clinical application of Therapeutic Plasma Exchange (TPE), also known as apheresis.
We discuss:
• What TPE is and how it works
• ASFA guideline categories and clinical evidence
• TPE in Guillain-Barré Syndrome, PANS/PANDAS, Myasthenia Gravis
• IVIG combination therapy
• The AMBAR Alzheimer’s trial results
• Safety, risks & outpatient candidacy
• Emerging research in aging and inflammatory load reduction
TPE works by removing harmful plasma components including antibodies, toxins, and neuroinflammatory proteins. While it does not reverse existing neurological damage, research suggests it may help slow disease progression in certain patient populations.
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