Ask Dr. Nick
On today’s episode, Dr. Nick talks about the role of the brain-gut-microbiome axis in depression. Depression has classically been thought of as a disorder of neurotransmitters (signals in the brain); however, over the last decade, more research has shown that inflammation and metabolic problems can cause depression. The gut contains a microbiome full of bacteria and viruses that help our internal ecosystem function properly. When the microbiome becomes affected by poor diet, stress, infections, and antibiotics, it can cause dysregulation or dysbiosis. Gut dysbiosis can affect the brain and its signaling via the gut-brain axis leading to depression symptoms. For this reason, there are many other therapies that can be used to prevent and treat depression. Check out the video for more in depth information on the brain-gut role in depression!
Chang L, Wei Y, Hashimoto K. Brain-gut-microbiota axis in depression: A historical overview and future directions. Brain Res Bull. 2022;182:44-56.
